Cellular Senescence and Tumor Suppression

Number of page: 272
Author: edited by Peter D. Adams, John M. Sedivy
Publisher: Springer Science & Business Media
Rating:
Category: Medical

As cells mature they naturally stop dividing and enter a period called senescence. But cellular senescence can also be induced prematurely by certain oncogenes involved in cancer development. Cellular senescence, a growth-arrest program that limits the lifespan of mammalian cells and prevents unlimited cell proliferation, is attracting considerable interest because of its links to tumor suppression.

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